Publications

Full Kang lab bibliography

(URL: https://www.ncbi.nlm.nih.gov/myncbi/sung%20ung.kang.1/bibliography/public/)

2021

Lee H, Lee JJ, Park NY, Dubey SK, Kim T, Ruan K, Lim SB, Park SH, Ha S, Kovlyagina I, Kim KT, Kim S, Oh Y, Kim H, Kang SU, Song MR, Lloyd TE, Maragakis NJ, Hong YB, Eoh H, Lee G. Multi-omic analysis of selectively vulnerable motor neuron subtypes implicates altered lipid metabolism in ALS. Nat Neurosci. 2021 Dec;24(12):1673-1685.

Seo BA, Kim D, Hwang H, Kim MS, Ma SX, Kwon SH, Kweon SH, Wang H, Yoo JM, Choi S, Kwon SH, Kang SU, Kam TI, Kim K, Karuppagounder SS, Kang BG, Lee S, Park H, Kim S, Yan W, Li YS, Kuo SH, Redding-Ochoa J, Pletnikova O, Troncoso JC, Lee G, Mao X, Dawson VL, Dawson TM, Ko HS. TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson's disease. Neuron. 2021 Dec 1;109(23):3758-3774.e11

Yazar V, Kang SU, Ha S, Dawson VL, Dawson TM. Integrative genome-wide analysis of dopaminergic neuron-specific PARIS expression in Drosophila dissects recognition of multiple PPAR-γ associated gene regulation. Sci Rep. 2021 Nov 2;11(1):21500.

Jo A, Lee Y, Kam TI, Kang SU, Neifert S, Karuppagounder SS, Khang R, Kang H, Park H, Chou SC, Oh S, Jiang H, Swing DA, Ham S, Pirooznia S, Umanah GKE, Mao X, Kumar M, Ko HS, Kang HC, Lee BD, Lee YI, Andrabi SA, Park CH, Lee JY, Kim H, Kim H, Kim H, Cho JW, Paek SH, Na CH, Tessarollo L, Dawson VL, Dawson TM, Shin JH. PARIS farnesylation prevents neurodegeneration in models of Parkinson's disease. Sci Transl Med. 2021 Jul 28;13(604)

2020

Lim SB, Dawson VL, Dawson TM, Kang SU. ACE2-expressing endothelial cells in aging mouse brain. J Brain Res 2020;3:2.

Sharma A, Lee S, Kim H, Yoon H, Ha S, Kang SU. Molecular Crosstalk Between Circadian Rhythmicity and the Development of Neurodegenerative Disorders. Front Neurosci. 2020;14:844.

Pirooznia SK, Yuan C, Khan MR, Karuppagounder SS, Wang L, Xiong Y, Kang SU, Lee Y, Dawson VL, Dawson TM. PARIS induced defects in mitochondrial biogenesis drive dopamine neuron loss under conditions of parkin or PINK1 deficiency. Mol Neurodegener. 2020 Mar 5;15(1):17.

Agarwal A, Park S, Ha S, Kwon JS, Khan MR, Kang BG, Dawson TM, Dawson VL, Andrabi SA, Kang SU.Quantitative mass spectrometric analysis of the mouse cerebral cortex after ischemic stroke. PLoS One. 2020;15(4):e0231978.

2019 - (Assistant Professor; Dept. of Neurology, Johns Hopkins Medicine; Institute for Cell Engineering)

Kang SU, Park JT. Functional evaluation of alternative splicing in the FAM190A gene. Genes Genomics. 2019 Feb;41(2):193-199.

Moon HY, Javadi S, Stremlau M, Yoon KJ, Becker B, Kang SU, Zhao X, van Praag H. Conditioned media from AICAR-treated skeletal muscle cells increases neuronal differentiation of adult neural progenitor cells. Neuropharmacology. 2019 Feb;145(Pt A):123-130.

2014.July-2019 (Research Associate)

Yun SP, Kam TI, Panicker N, Kim S, Oh Y, Park JS, Kwon SH, Park YJ, Karuppagounder SS, Park H, Kim S, Oh N, Kim NA, Lee S, Brahmachari S, Mao X, Lee JH, Kumar M, An D, Kang SU, Lee Y, Lee KC, Na DH, Kim D, Lee SH, Roschke VV, Liddelow SA, Mari Z, Barres BA, Dawson VL, Lee S, Dawson TM, Ko HS.Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease. Nat Med. 2018 Jul;24(7):931-938.

Xiong Y, Neifert S, Karuppagounder SS, Liu Q, Stankowski JN, Lee BD, Ko HS, Lee Y, Grima JC, Mao X, Jiang H, Kang SU, Swing DA, Iacovitti L, Tessarollo L, Dawson TM, Dawson VL. Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1635-1640.

Lee Y*, Stevens DA*, Kang SU*, Jiang H, Lee YI, Ko HS, Scarffe LA, Umanah GE, Kang H, Ham S, Kam TI, Allen K, Brahmachari S, Kim JW, Neifert S, Yun SP, Fiesel FC, Springer W, Dawson VL, Shin JH, Dawson TM. PINK1 Primes Parkin-Mediated Ubiquitination of PARIS in Dopaminergic Neuronal Survival. Cell Rep. 2017 Jan 24;18(4):918-932.

Mao X, Ou MT, Karuppagounder SS, Kam TI, Yin X, Xiong Y, Ge P, Umanah GE, Brahmachari S, Shin JH, Kang HC, Zhang J, Xu J, Chen R, Park H, Andrabi SA, Kang SU, Gonçalves RA, Liang Y, Zhang S, Qi C, Lam S, Keiler JA, Tyson J, Kim D, Panicker N, Yun SP, Workman CJ, Vignali DA, Dawson VL, Ko HS, Dawson TM. Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3. Science. 2016 Sep 30;353(6307).

Jiang H*, Kang SU*, Zhang S, Karuppagounder S, Xu J, Lee YK, Kang BG, Lee Y, Zhang J, Pletnikova O, Troncoso JC, Pirooznia S, Andrabi SA, Dawson VL, Dawson TM. Adult Conditional Knockout of PGC-1α Leads to Loss of Dopamine Neurons. eNeuro. 2016 Jul-Aug;3(4).

Stevens DA, Lee Y, Kang HC, Lee BD, Lee YI, Bower A, Jiang H, Kang SU, Andrabi SA, Dawson VL, Shin JH, Dawson TM. Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration. Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):11696-701.

2011-2014.June (Post-Doctoral fellow; Johns Hopkins Univ. School of medicine)

Lee Y, Karuppagounder SS, Shin JH, Lee YI, Ko HS, Swing D, Jiang H, Kang SU, Lee BD, Kang HC, Kim D, Tessarollo L, Dawson VL, Dawson TM. Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss. Nat Neurosci. 2013 Oct;16(10):1392-400.

Pajer V, Tiboldi A, Bae N, Li K, Kang SU, Hopp B, Kolozsvári L, Lubec G, Nógrádi A. The molecular background of the differential UV absorbance of the human lens in the 240-400 nm range. Photochem Photobiol. 2013 Jul-Aug;89(4):856-63.

Lee JC, Kang SU, Jeon Y, Park JW, You JS, Ha SW, Bae N, Lubec G, Kwon SH, Lee JS, Cho EJ, Han JW.Protein L-isoaspartyl methyltransferase regulates p53 activity. Nat Commun. 2012 Jun 26;3:927.

2005-2010 (Doctoral Courses; Medical School of Vienna, Austria; Dr.Med.Sc)

Kang SU, Heo S, Lubec G. In-gel total protein quantification using a ninhydrin-based method. Amino Acids. 2013 Oct;45(4):1003-13.

Myllykoski M, Itoh K, Kangas SM, Heape AM, Kang SU, Lubec G, Kursula I, Kursula P. The N-terminal domain of the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase: direct molecular interaction with the calcium sensor calmodulin. J Neurochem. 2012 Nov;123(4):515-24.

Kang SU, Heo S, Lubec G. Mass spectrometric analysis of GABAA receptor subtypes and phosphorylations from mouse hippocampus. Proteomics. 2011 Jun;11(11):2171-81

Kang SU, Lubec G. Determination of in-gel protein concentration by a ninhydrin-based method.Proteomics. 2011 Feb;11(3):481-4.

Patil SS, Boddul SV, Schlick K, Kang SU, Zehetmayer S, Höger H, Lubec G. Differences in hippocampal protein levels between C57Bl/6J, PWD/PhJ, and Apodemus sylvaticus are paralleled by differences in spatial memory. Hippocampus. 2011 Jul;21(7):714-23

Burgos M, Fradejas N, Calvo S, Kang SU, Tranque P, Lubec G. A proteomic analysis of PKCε targets in astrocytes: implications for astrogliosis. Amino Acids. 2011 Feb;40(2):641-51

Heo S, Kang SU, Oehler R, Pollak A, Lubec G. Mass spectrometrical analysis of the mitochondrial carrier Aralar1 from mouse hippocampus. Electrophoresis. 2010 Jun;31(11):1813-21

Li L, Mauric V, Zheng JF, Kang SU, Patil S, Höger H, Lubec G. Olfactory bulb proteins linked to olfactory memory in C57BL/6J mice. Amino Acids. 2010 Aug;39(3):871-86.

Afjehi-Sadat L, Brejnikow M, Kang SU, Vishwanath V, Walder N, Herkner K, Redl H, Lubec G. Differential protein levels and post-translational modifications in spinal cord injury of the rat. J Proteome Res. 2010 Mar 5;9(3):1591-7

Majava V, Wang C, Myllykoski M, Kangas SM, Kang SU, Hayashi N, Baumgärtel P, Heape AM, Lubec G, Kursula P. Structural analysis of the complex between calmodulin and full-length myelin basic protein, an intrinsically disordered molecule. Amino Acids. 2010 Jun;39(1):59-71

Kang SU, Fuchs K, Sieghart W, Pollak A, Csaszar E, Lubec G. Gel-based mass spectrometric analysis of a strongly hydrophobic GABAA-receptor subunit containing four transmembrane domains. Nat Protoc. 2009;4(7):1093-102.

Kang SU, Zhang M, Burgos M, Lubec G. Mass spectrometrical characterisation of mouse and rat synapsin isoforms 2a and 2b. Amino Acids. 2010 Apr;38(4):1131-43.

Kang SU, Lubec G. Complete sequencing of GABAA receptor subunit beta 3 by a rapid technique following in-gel digestion of the protein. Electrophoresis. 2009 Jun;30(12):2159-67.

Ahmed KE, Chen WQ, John JP, Kang SU, Lubec G. Complete sequencing of the recombinant granulocyte-colony stimulating factor (filgrastim) and detection of biotinylation by mass spectrometry. Amino Acids. 2010 Apr;38(4):1043-9

Sunyer B, An G, Kang SU, Höger H, Lubec G. Strain-dependent hippocampal protein levels of GABA(B)-receptor subunit 2 and NMDA-receptor subunit 1. Neurochem Int. 2009 Sep;55(4):253-6.

Sunyer B, Diao WF, Kang SU, An G, Boddul S, Lubec G. Cognitive enhancement by SGS742 in OF1 mice is linked to specific hippocampal protein expression. J Proteome Res. 2008 Dec;7(12):5237-53

Baer AS*, Syed YA*, Kang SU*, Mitteregger D, Vig R, Ffrench-Constant C, Franklin RJ, Altmann F, Lubec G, Kotter MR. Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling. Brain. 2009 Feb;132(Pt 2):465-81.

Gruber-Olipitz M, Ströbel T, Kang SU, John JP, Grotzer MA, Slavc I, Lubec G. Neurotrophin 3/TrkC-regulated proteins in the human medulloblastoma cell line DAOY. Electrophoresis. 2009 Feb;30(3):540-9.

Azizi AA, Kang SU, Freilinger A, Gruber-Olipitz M, Chen WQ, Yang JW, Hengstschläger M, Slavc I, Lubec G. Mitosis-dependent protein expression in neuroblastoma cell line N1E-115. J Proteome Res. 2008 Aug;7(8):3412-22

Kang SU*, Fuchs K*, Sieghart W, Lubec G. Gel-based mass spectrometric analysis of recombinant GABA(A) receptor subunits representing strongly hydrophobic transmembrane proteins. J Proteome Res. 2008 Aug;7(8):3498-506.

Chen WQ*, Kang SU*, Lubec G. Protein profiling by the combination of two independent mass spectrometry techniques. Nat Protoc. 2006;1(3):1446-52.

Yang JW, Kang SU, Engidawork E, Rodrigo R, Felipo V, Lubec G. Mass spectrometrical analysis of galectin proteins in primary rat cerebellar astrocytes. Neurochem Res. 2006 Jul;31(7):945-55.

Bierczynska-Krzysik A*, Kang SU*, Silberrring J, Lubec G. Mass spectrometrical identification of brain proteins including highly insoluble and transmembrane proteins. Neurochem Int. 2006 Aug;49(3):245-55.