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SUNG-UNG KANG Dr.Med.Sc

Assistant Professor
Institute for Cell Engineering (Neuroregeneration program)
Department of Neurology;
The Johns Hopkins School of Medicine, Baltimore
(MRB Rm753; e-mail: skang34(at)jhmi.edu)

About Kang's Lab

Kang's Lab aims to identify the key molecular hubs causing selective vulnerability in Parkinson's disease (PD) and Alzheimer's Disease (AD), which are crucial to identify discriminative markers for diagnosis and new treatment modalities. A hypothesis "Gut-Brain Axis" associated with DNA damages and Sleep disorders, known as a bidirectional complexity triggering the progressive neurodegenerations, has been tested using experimental data obtained from genetically associated transgenic mice as well as formidable data generated from human post-mortem tissues. To further provide a comprehensive perspective, we have been developing unique bioinformatic algorithms and building data structure for deep learning-based genomic data integration. State-of-the-art technologies incl. in-house developed single-cell genomics (HiF-snRNAseq; High Efficient single nuclei RNA sequencing), spatial genomics (10x Genomics), metagenomics (Illumina), and epigenomics including Cut&Tag, WGBS, ATAC-seq, Hi-C have been applied for data collection. 

Keywords

#Neurodegenerative diseases, #Parkinson's disease (PD), #Alzheimer's disease (AD), #Gut-Brain axis, #Single-cell genomics, #Epigenomics, #Big Data, #Deep learning, #Molecular Circadian rhythms, #Transgenic animals, #Identification of cell-type specific diagnostic markers

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Post-mortem brains
COVID19 brains
ACD multiplex
Single-cell genomics
Gut injection
 miRNA
Stroke
Drosophila TRAP Control
Sung Ung Kang Picture.png

Lab space
& state of the art research equipments

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#Lab, #ICE, #JHMI  Media Appearances

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Inclusion is in our DNA | Johns Hopkins Founding Letter

Inclusion is in our DNA | Johns Hopkins Founding Letter

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Welcome to the Johns Hopkins Institute for Cell Engineering (ICE)

Welcome to the Johns Hopkins Institute for Cell Engineering (ICE)

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125 Years of the Johns Hopkins School of Medicine

125 Years of the Johns Hopkins School of Medicine

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Johns Hopkins Medicine 2019 Nobel Prize Celebrations | Gregg Semenza

Johns Hopkins Medicine 2019 Nobel Prize Celebrations | Gregg Semenza

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The Neuroregeneration Program at Johns Hopkins’ Institute for Cell Engineering

The Neuroregeneration Program at Johns Hopkins’ Institute for Cell Engineering

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MARCC Construction

MARCC Construction

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U.S. News and World Report's Best Hospital 2020-21 Update from Dr. Justin McArthur

U.S. News and World Report's Best Hospital 2020-21 Update from Dr. Justin McArthur

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The Institute for Cell Engineering (ICE) at Johns Hopkins

The Institute for Cell Engineering (ICE) at Johns Hopkins

02:25
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© 2021 Created by Dr.SUNG UNG KANG 

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